eamdacademy.org-rIYB-1793369135-c644776987 1793369135 Eurasian Academy of Medicine and Dentistry info@eamdacademy.org Eurasian Academy of Medicine and Dentistry Journal of Applied Pharmaceutical Technologies and Systems J Appl Pharm Technol Syst 3149-9589 2024 3 2 Fatima Zahra Amrani Youssef Benali Samira El-Haddad 2024 10.68159/c644776987 https://eamdacademy.org/pub/journal/3/article/c644776987 Seevagan T, Hulligan S, Phull J, Aboumarzouk OM. Testes structure and function. Blandy’s Urol. 2019:729-39. Foster RA. Male Reproductive System1, in Pathologic Basis of Veterinary Disease (Sixth Edition), eds. J.F. Zachary & J.F. Zachary. 2017;Chapter 19:1194-222. El Arem A, Lahouar L, Saafi EB, Thouri A, Ghrairi F, Houas Z, et al. Dichloroacetic acid-induced testicular toxicity in male rats and the protective effect of date fruit extract. BMC Pharmacol Toxicol. 2017;18(1):1-9. Makhadumsab T. Reproductive Toxicology: an update, in male reproductive anatomy, eds. C.G. Shridhar & C.G. Shridhar. (Rijeka). 2022; Chapter 5. Del Río E, Rojo L, Vilanova E. Carbon tetrachloride,” in encyclopedia of toxicology (Third Edition), eds. P. Wexler & P. Wexler. (Oxford). 2014:687-90. Al Amin ASM, Menezes RG. Carbon tetrachloride toxicity continuing education activity. StatPearls - NCBI Bookshelf, 2021. Rahman MM, Muse AY, Khan DI, Ahmed IH, Subhan N, Reza HM, et al. Apocynin prevented inflammation and oxidative stress in carbon tetra chloride induced hepatic dysfunction in rats. Biomed Pharmacother. 2017;92:421-8. Abdel-Kader MS, Abulhamd AT, Hamad AM, Alanazi AH, Ali R, Alqasoumi SI. Evaluation of the hepatoprotective effect of combination between hinokiflavone and Glycyrrhizin against CCl4 induced toxicity in rats. Saudi Pharm J. 2018;26(4):496-503. Elsawy H, Badr GM, Sedky A, Abdallah BM, Alzahrani AM, Abdel-Moneim AM. Rutin ameliorates carbon tetrachloride (CCl4)-induced hepatorenal toxicity and hypogonadism in male rats. Peer J. 2019;7:e7011. Moufid A, Eddouks M. Artemisia herba alba: a popular plant with potential medicinal properties. Pak J Biol Sci. 2012;15(24):1152-9. Mohamed AE, El-Sayed M, Hegazy ME, Helaly SE, Esmail AM, Mohamed NS. Chemical constituents and biological activities of Artemisia herba-alba. Rec Nat Prod. 2010;4(1):1-25. Belhattab R, Amor L, Barroso JG, Pedro LG, Figueiredo AC. Essential oil from Artemisia herba-alba Asso grown wild in Algeria: variability assessment and comparison with an updated literature survey. Arab J Chem. 2014;7(2):243-51. Chadwick M, Trewin H, Gawthrop F, Wagstaff C. Sesquiterpenoids lactones: benefits to plants and people. Int J Mol Sci. 2013;14(6):12780-805. Núñez F, Chipchase MD, Clarke AR, Melton DW. Nucleotide excision repair gene (ERCC1) deficiency causes G2 arrest in hepatocytes and a reduction in liver binucleation: the role of p53 and p21. FASEB J. 2000;14(9):1073-82. Köberle B, Brenner W, Albers A, Usanova S, Thüroff JW, Kaina B. ERCC1 and XPF expression in human testicular germ cell tumors. Oncol Rep. 2010;23(1):223-7. Sahreen S, Khan MR, Khan RA, Shah NA. Effect of Carissa opaca leaves extract on lipid peroxidation, antioxidant activity and reproductive hormones in male rats. Lipids Health Dis. 2013;12:90. Hashem AS. Defensive impact of propolis against CCl4 actuated rats’ testicular damage. J Adv Vet Anim Res. 2021;8(1):70. Ijaz MU, Iqbal M, Iqbal MA, Ashraf A, Al-Ghanim KA, Al-Misned F, et al. In vivo antioxidant efficacy and therapeutic potential of Artemisia brevifolia leaves extract against CCl4-induced reproductive damages in male albino rats. J King Saud Univ-Sci. 2022;34(2):101816. Abdel Moneim AE. Prevention of carbon tetrachloride (CCl4)-induced toxicity in testes of rats treated with Physalis peruviana L. fruit. Toxicol Ind Health. 2016;32(6):1064-73. Abbas R, Iqbal Z, Mansoor M, Sindhu Z, Zia M, Khan J. Role of natural antioxidants for the control of coccidiosis in poultry. Pak Vet J. 2013;33:401-7. Ojo OA, Ojo AB, Ajiboye B, Fadaka A, Imiere OD, Adeyonu O, et al. Protective influence of Ficus asperifolia Miq leaf extract on carbon tetrachloride (CCl4)-induced testicular toxicity in rat’s testes. J Appl Pharm Sci. 2016;6(6):37-41. Khan RA. Protective effects of Launaea procumbens on rat testis damage by CCl4. Lipids Health Dis. 2012;11(1):1-8. Sahreen S, Khan MR, Khan RA. Ameliorating effect of various fractions of Rumex hastatus roots against hepato- and testicular toxicity caused by CCl4. Oxid Med Cell Longev. 2013;2013:325406. Schärer OD. Nucleotide excision repair in eukaryotes. Cold Spring Harb Perspect Biol. 2013;5(10):a012609. Manandhar M, Boulware KS, Wood RD. The ERCC1 and ERCC4 (XPF) genes and gene products. Gene. 2015;569(2):153-61. Soares S, Nogueira A, Coelho A, Assis J, Pereira D, Bravo I, et al. Relationship between clinical toxicities and ERCC1 rs3212986 and XRCC3 rs861539 polymorphisms in cervical cancer patients. Int J Biol Markers. 2018;33(1):116-23. Duran G, Aguín S, Cruz R, Barros F, Giráldez JM, Bernárdez B, et al. Association of GSTP1 and ERCC1 polymorphisms with toxicity in locally advanced head and neck cancer platinum‐based chemoradiotherapy treatment. Head Neck. 2019;41(8):2704-15. Jacobsen F, Taskin B, Melling N, Sauer C, Wittmer C, Hube-Magg C, et al. Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer. BMC Cancer. 2017;17(1):1-1. Samad A, Ijaz MU, Ashraf A, Sajid M, Imran M, Abbas K, et al. Methanolic extract of Nepeta paulsenii as an ameliorative agent against CCl4 induced testicular damage in male albino rats. J King Saud Univ Sci. 2020;32(1):1168-74.